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["Table 1. Clinical and molecular characteristics of patients with gliomas (n=1502)"]
["Variables",null,"N(%)"]
["Gender (n=1502)","male","875(58.3%)"]
[null,"female","627(41.7%)"]
["WHO grade (n=1502)","Ⅰ","137(9.1%)"]
[null,"Ⅱ","530(35.3%)"]
[null,"Ⅲ","381(25.4%)"]
[null,"Ⅳ","454(30.2%)"]
["Histology (n=1502)","Diffuse astrocytoma","180(12.0%)"]
[null,"Anaplastic astrocytoma","242(16.1%)"]
[null,"Glioblastoma","446(29.7%)"]
[null,"Diffuse midline glioma,H3K27M-mutant","8(0.5%)"]
[null,"Oligodendroglioma","94(6.3%)"]
[null,"Anaplastic oligodendroglioma","54(3.6%)"]
[null,"Oligoastrocytoma","75(5.0%)"]
[null,"Anaplastic oligoastrocytoma","38(2.5%)"]
[null,"Pilocytic astrocytoma","68(4.5%)"]
[null,"Subependymal giant cell astrocytoma","2(0.1%)"]
[null,"Pleomorphic xanthoastrocytoma","13(0.9%)"]
[null,"Anaplastic pleomorphic xanthoastrocytoma","2(0.1%)"]
[null,"Subependymoma","2(0.1%)"]
[null,"Myxopapillary ependymoma","10(0.7%)"]
[null,"Ependymoma","160(10.7%)"]
[null,"Anaplastic ependymoma","39(2.6%)"]
[null,"Angiocentric glioma","2(0.1%)"]
[null,"Chordoid glioma of the third ventricle","1(0.1%)"]
[null,"Choroid plexus papilloma","22(1.5%)"]
[null,"Atypical choroid plexus papilloma","5(0.3%)"]
[null,"Ganglioglioma","31(2.1%)"]
[null,"Anaplastic ganglioglioma","7(0.5%)"]
[null,"Desmoplastic infantile astrocytoma and  ganglioglioma","1(0.1%)"]
["Glioma cell differentiation direction (n=1502)","Astrocyte  origin","953(63.4%)"]
[null,"Oligodendrocyte origin","151(10.1%)"]
[null,"Source of ependymal cells","211(14.0%)"]
[null,"Hybrid cell source","149(9.9%)"]
[null,"Other cell sources","38(2.5%)"]
["Tumor size(n=1249)","0-4cm","448(29.8%)","mean:4.9cm (SD=2.0cm)"]
[null,"4-6cm","493(32.8%)"]
[null,"＞6cm","308(20.5%)"]
["Anatomic Location(n=856)","frontal lobe","306(35.75%)"]
[null,"temporal lobe","149(17.41%)"]
[null,"parietal lobe","43(5.02%)"]
[null,"occipital lobe","17(1.99%)"]
[null,"insular lobe","13(1.52%)"]
[null,"sellar region","18(2.10%)"]
[null,"ventricle","110(12.85%)"]
[null,"basal ganglia region","15(1.75%)"]
[null,"brain stem","37(4.32%)"]
[null,"corpus callosum","5(0.58%)"]
[null,"lipochoristomas of the cerebellopontine","6(0.70%)"]
[null,"cranial nerves","8(0.93%)"]
[null,"pineal","27(3.15%)"]
[null,"hypothalamus","47(5.49%)"]
[null,"cerebellum","48(5.61%)"]
[null,"other brain","7(0.82%)"]
["GFAP(n=1120)","unexpression","9(0.8%)"]
[null,"expression","1111(99.2%)"]
["EMA(n=941)","unexpression","721(76.6%)"]
[null,"expression","220(23.4%)"]
["MGMT(n=969)","unexpression","369(38.1%)"]
[null,"expression","600(61.9%)"]
["wt-p53(n=333)","0-10%","127(38.1%)"]
[null,"10-30%","69(20.7%)"]
[null,"30-60%","57(17.1%)"]
[null,"＞60%","80(24.0%)"]
["NeuN(n=890)","unexpression","508(57.1%)"]
[null,"expression","382(42.9%)"]
["Oligo2(n=894)","unexpression","128(14.3%)"]
[null,"expression","766(85.7%)"]
["EGFR(n=847)","unexpression","90(10.6%)"]
[null,"expression","757(89.4%)"]
["VEGF(n=847)","unexpression","84(9.9%)"]
[null,"expression","763(90.1%)"]
["IDH1(n=725)","wt","436(60.1%)"]
[null,"mut","289(39.9%)"]
["ki-67(n=1139)","0-10%","585(51.4%)"]
[null,"＞10%","554(48.6%)"]
["1p/19q(N=212)","intact","150(70.8%)"]
[null,"codeleted","32(15.1%)"]
[null,"1p deleted","14(6.7%)"]
[null,"19q deleted","16(7.5%)"]
["ATRX(n=227)","mutant","12(5.3%)"]
[null,"wild type","215(94.7%)"]
["PR(n=38)","unexpression","34(89.5%)"]
[null,"expression","4(10.5%)"]
["LCA(n=26)","unexpression","23(88.5%)"]
[null,"expression","3(11.5%)"]
["Actin(n=31)","unexpression","21(67.7)"]
[null,"expression","10(32.3%)"]
["NF(n=119)","unexpression","64(53.8%)"]
[null,"expression","55（46.2%）"]
["CgA(n=99)","unexpression","89(89.9%)"]
[null,"expression","10(10.1%)"]
["CD3(n=27)","unexpression","21(77.8%)"]
[null,"expression","6(22.2%)"]
["CD20(n=30)","unexpression","28(93.3%)"]
[null,"expression","2(6.7%)"]
["CK(n=156)","unexpression","126(80.8%)"]
[null,"expression","30(19.2%)"]
["CD34(n=110)","unexpression","45(40.9%)"]
[null,"expression","65(59.1%)"]
["CD30(n=12)","unexpression","10(83.3%)"]
[null,"expression","2(16.7%)"]
["CD31(n=17)","unexpression","10(58.8%)"]
[null,"expression","7(41.2%)"]
["CD68(n=19)","unexpression","7(36.8%)"]
[null,"expression","12(63.2%)"]
["Syn(n=236)","unexpression","74(31.4%)"]
[null,"expression","162(68.6%)"]
["S-100(n=238)","unexpression","32(13.4%)"]
[null,"expression","206(86.6%)"]
["Vimentin(n=116)","unexpression","8(6.9%)"]
[null,"expression","108(93.1%)"]
["BrafV600E(n=89)","unexpression","79(88.8%)"]
[null,"expression","10(11.2%)"]
["H3K27M(n=96)","unexpression","82(85.4%)"]
[null,"expression","14(14.6%)"]
["MRP(n=140)","unexpression","34(24.3%)"]
[null,"expression","106(75.7%)"]
["LRP(n=138)","unexpression","84(60.9%)"]
[null,"expression","54(39.1%)"]
["Her2(n=139)","unexpression","135(97.1%)"]
[null,"expression","4(2.9%)"]
["Bcl2(n=149)","unexpression","87(58.4%)"]
[null,"expression","62(41.6%)"]
["TS(n=134)","unexpression","59(44.0%)"]
[null,"expression","75(56.0%)"]
["PgP(n=138)","unexpression","53(38.4%)"]
[null,"expression","85(61.6%)"]
["TOPII(n=152)","unexpression","44(28.9%)"]
[null,"expression","108(71.1%)"]
["GST-π(n=135)","unexpression","67(49.6%)"]
[null,"expression","68(50.4%)"]
["CIC(n=39)","unexpression","4(10.3%)"]
[null,"expression","35(89.7%)"]
["FUBP1(n=41)","unexpression","2(4.9%)"]
[null,"expression","39(95.1%)"]
["Desmin(n=27)","unexpression","24(88.9%)"]
[null,"expression","3(11.1%)"]
["NSE(n=46)","unexpression","11(23.9%)"]
[null,"expression","35(76.1%)"]